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Introduction : Formation of blood clot to arrest bleeding is a natural and essential process given to mankind. Like platelets, there are many other clotting factors in the blood which help in blood coagulation.

Effects : Heparin is available in injection form. It prevents activation of these blood clotting factors and keep blood thin.

Uses : 

  1. Unstable angina
  2. Heart attack
  3. During angioplasty
  4. During coronary artery bypass surgery

Dose : 

Inj. Heparin : 500 – 1000 unit / hour as intravenous infusion

Inj. Low Molecular Weight Heparin (LMWH) : 0.3 – 0.6 ml Subcutaneous (under the skin) : Twice a day

Inj. Bivalirudin : Intravenous infusion

Side effects :

  1. Bleeding
  2. Disturbance in the functioning of platelets

Many researches of last several years proved that LMWH injections are more effective, safe and comfortable for the patient as compared to Heparin.