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Introduction : Adequate number of normally functioning platelets is required to maintain the proper flow of blood in arteries and veins.Innumerable micro blood vessels get ruptured and new ones are generated every moment due to degeneration and wear and tear of daily life. A protective process of blood coagulation (creating a plug of blood clot at that site) exists in the human body to prevent or arrest bleeding. Platelets are very crucial to initiate this process. Thus, platelets keep on repairing arteries and veins and prevent bleeding.

Effects : Antiplatelet medicines work on these platelets and prevent them from forming a blood clot by sticking with each other. Formation of a blood clot inside the narrowed coronary arteries causes unstable angina or heart attack. Recurrence of clotting of blood can be prevented by giving antiplatelet medicines. Many scientific researches have proved that future risk of heart attack, paralysis and death is greatly reduced by this medicine when it is given to persons with blockage in the arteries.

Uses : 

  1. Stable angina
  2. Unstable angina
  3. Heart attack
  4. Ischemic stroke
  5. After angioplasty and placing a stent in any artery
  6. After coronary artery bypass surgery

Dose :

Tab Aspirin : 325 mg first dose, followed by 75 – 150 mg per day

Tab Clopidogrel : 300 – 600 mg first dose, followed by 75 mg per day

Tab Prasugrel : 60 mg first dose, followed by 10 mg per day

Tab Ticagrelor : 180 mg first dose, followed by 90 mg twice a day

It is utmost necessary to know two things before prescribing this medicine, ‘whether a person has suffered from bleeding any time in the past’ and ‘whether there is a significant possibility of bleeding due to any reason in future.’

All medicines should be taken as per the scientific advice and under the care of the cardiologist.

Side effects :

  1. Bleeding
  2. Allergy
  3. Acidity